PDF in Oftalmologia in italiano/inglese (articoli presenti: 1052)

Tear Meniscus Analysis with Fourier-Domain Optical Coherence Tomography in Keratoconus


Tear Meniscus Analysis with Fourier-Domain Optical Coherence Tomography in Keratoconus


Area Tematica : cornea

Comparison of Macular Thickness in Patients with Keratoconus and Control Subjects Using the Cirrus HD-OCT


Comparison of Macular Thickness in Patients with Keratoconus and Control Subjects Using the Cirrus HD-OCT


Area Tematica : cornea

Keratoconus Diagnosis with An Optical Coherence Tomography- Based Pachymetric Scoring System


Keratoconus Diagnosis with An Optical Coherence Tomography- Based Pachymetric Scoring System


Area Tematica : cornea

Comparison of Corneal Epithelial Thickness Measurement Between Fourier-Domain OCT and Very High-Frequency Digital Ultrasound


Comparison of Corneal Epithelial Thickness Measurement Between Fourier-Domain OCT and Very High-Frequency Digital Ultrasound


Area Tematica : cornea

Assessing progression of keratoconus: novel tomographic determinant


Assessing progression of keratoconus: novel tomographic determinant


Area Tematica : cornea

Evaluation of scleral and corneal thickness in keratoconus patients

Abstract Purpose:


To identify corneal epithelial- and stromal-thickness distribution patterns in keratoconus using spectral-domain optical coherence tomography (SD-OCT).

Patients and Methods: We analyzed SD-OCT findings in 20 confirmed cases of keratoconus (group 1) and in 20 healthy subjects with corneal astigmatism $2 D (group 2). Epithelial and stromal thicknesses were measured at 11 strategic locations along the steepest and flattest meridians, previously located by corneal topography. Vertical mirrored symmetry superimposition was used in the statistical analysis. 

Results: The mean maximum keratometry measurements in groups 1 and 2 were 47.962.9 D (range, 41.8–52.8) and 45.661.1 D (range, 42.3–47.5), respectively, with mean corneal cylinders of 3.362.2 D (range, 0.5–9.5) and 3.661.2 D (range, 2.0–6.4), respectively. The mean epithelial thickness along the steepest meridian in group 1 was the lowest (37.464.4 mm) at 1.2 mm inferotemporally and the highest (59.364.4 mm) at 1.4 mm supranasally from the corneal vertex. There was only a small deviation in thickness along the steepest meridian in group 2, as well as along the flattest meridians in both groups. The stromal thickness distribution in the two groups was similar to the epithelial, while the stromal thickness was generally lower in group 1 than in group 2.

Conclusions: SD-OCT provides details about the distribution of corneal epithelial and stromal thicknesses. The epithelium and stroma in keratoconic eyes were thinner inferotemporally and thicker supranasally compared with control eyes. The distribution pattern was more distinct in epithelium than in stroma. This finding may help improve the early diagnosis of keratoconus.


Evaluation of scleral and corneal thickness in keratoconus patients


Area Tematica : cornea

Spectral-Domain OCT Analysis of Regional Epithelial Thickness Profiles in Keratoconus, Postoperative Corneal Ectasia, and Normal Eyes


Spectral-Domain OCT Analysis of Regional Epithelial Thickness Profiles in Keratoconus, Postoperative Corneal Ectasia, and Normal Eyes


Area Tematica : cornea

Global Consensus on Keratoconus and Ectatic Diseases


Global Consensus on Keratoconus and Ectatic Diseases


Area Tematica : cornea

Parameters to Document Progression of Keratoconus

The Keratoconus Expert Group, conceived and established by Jérôme C. Vryghem, MD, is a vibrant group of invited international corneal experts with special interest in keratoconus. Prior to the meeting of the European Society of Cataract and Refractive Surgeons (ESCRS) in October 2013, the group, in its fourth year, convened with a specific purpose to arrive at a consensus in three principal areas: 

(1) the criteria used to determine the progression of keratoconus,
 (2) when (and how) to perform corneal collagen crosslinking, 
and (3) the value of intrastromal corneal ring segments. 
I had the privilege and rather challenging job of chairing the section on establishing criteria for measuring the progression of keratoconus. I say challenging because, as you will see from the articles in this bonus feature—particularly those by A. John Kanellopoulos, MD, and Michael Belin, MD—there are considerable differences in opinion on this subject. Although there is general agreement about what should be considered progression, it is clear that more scientific study is required when it comes to measuring subtle progression. There are a number of variables at play, and each one is unique, with its own characteristics. Even data analysis using averages is fraught with problems, unless one has the luxury of access to 100% data in all eyes at all timeframes with similar criteria, including cessation of contact lens wear prior to evaluation. As Dr. Belin points out, most patients with keratoconus are dependent on hard contact lenses, and, as these lenses definitely affect anterior corneal shape, basing decisions mainly on anterior parameters carries risk of potential error. 
Requesting that patients with keratoconus keep their lenses out for 1 month in order to evaluate them properly is idealistic and probably overkill. Often, when there is considerable controversy, simple approaches are best. Dr. Belin’s approach is quite attractive: Corneal thickness and posterior elevation may be the best criteria to use, perhaps with the addition of corneal volumetric change. We may also need an alternative approach altogether, using a different method of diagrammatic presentation; Damien Gatinel, MD, has used a clever method in his Score software (Bausch + Lomb Technolas), which employs multiple variables to evaluate the risk of keratoconus in corneas prior to elective ablative refractive surgery. Getting back to basics, evaluating markers for keratconus is likely the ultimate tool, and Jesús Merayo, MD, PhD, reports on some of his work in this area, which looks interesting and promising. We hope you enjoy these articles, and we expect that you have your own individual opinions. Please do not hesitate to contact us—we would love to have the opportunity to publish your views.


Parameters to Document Progression of Keratoconus


Area Tematica : cornea

Protocollo Malattie Reumatologiche

INTRODUZIONE 

La reumatologia è un ambito complesso ove non sono utili esami di screening. I quadri di presentazione possono essere molteplici all’interno della stessa patologia, alcuni quadri iniziali possono essere comuni a patologie diverse; di conseguenza l’inquadramento nosologico e la diagnosi differenziale sono complessi e richiedono l’utilizzo di esami di laboratorio il cui risultato deve essere interpretato alla luce del sospetto clinico e del quadro sindromico generale. Va tenuto conto che una patologia reumatica evolve nel tempo creando problemi sempre nuovi e diversi sia al paziente che al medico curante e d’altra parte alcune delle patologie reumatiche più comuni come l’osteoartrosi, l’artrite reumatoide, l’artrite psoriasica ed il reumatismo fibromialgico possono essere sospettate senza test di laboratorio. Per contro, richiedere esami di laboratorio dovrebbe essere finalizzato a confermare o escludere una potenziale patologia reumatica ipotizzata alla visita clinica. Premesso ciò, il documento avrebbe l’intento di proporre l’utilizzo di alcuni esami di laboratorio utili all’inquadramento diagnostico e al monitoraggio della patologia in esame, tenendo conto della necessità di ottimizzare le risorse in una logica di appropriatezza prescrittiva. Si insiste sull’assunto che non si intende fornire schemi di valore assoluto ma indicazioni di massima applicabili con competenza clinica nei quadri di presentazione comune, fermo restando che nelle situazioni complesse, atipiche e inusuali il ragionamento clinico deve portare a cercare soluzioni appropriate al caso in oggetto. Considerando che il passaggio logico dai sintomi di presentazione all’ipotesi diagnostica si basa sull’anamnesi accurata, sull’esame obiettivo mirato e sull’inquadramento generale del sintomo nel quadro generale del paziente, la responsabilità del percorso diagnostico iniziale è chiaramente di competenza del Medico di Medicina Generale.


Protocollo Malattie Reumatologiche


Area Tematica : uveiti

Keratoconus / Ectasia Detection with the Oculus Pentacam: Belin / Ambrosio Enhanced Ectasia Display


Keratoconus / Ectasia Detection with the Oculus Pentacam: Belin / Ambrosio Enhanced Ectasia Display


Area Tematica : cornea

ND:YAG-LASER IRIDOTOMY: A LITERATURE REVIEW


ND:YAG-LASER IRIDOTOMY: A LITERATURE REVIEW


Area Tematica : glaucoma

Adaptive-optics SLO imaging combined with widefield OCT and SLO enables precise 3D localization of fluorescent cells in the mouse retina

Abstract: Adaptive optics scanning laser ophthalmoscopy (AO-SLO) has recently been used to achieve exquisite subcellular resolution imaging of the mouse retina. Wavefront sensing-based AO typically restricts the field of view to a few degrees of visual angle. As a consequence the relationship between AO-SLO data and larger scale retinal structures and cellular patterns can be difficult to assess.


 The retinal vasculature affords a largescale 3D map on which cells and structures can be located during in vivo imaging. Phase-variance OCT (pv-OCT) can efficiently image the vasculature with near-infrared light in a label-free manner, allowing 3D vascular reconstruction with high precision. We combined widefield pvOCT and SLO imaging with AO-SLO reflection and fluorescence imaging to localize two types of fluorescent cells within the retinal layers: GFPexpressing microglia, the resident macrophages of the retina, and GFPexpressing cone photoreceptor cells. We describe in detail a reflective afocal AO-SLO retinal imaging system designed for high resolution retinal imaging in mice. The optical performance of this instrument is compared to other state-of-the-art AO-based mouse retinal imaging systems. 

The spatial and temporal resolution of the new AO instrumentation was characterized with angiography of retinal capillaries, including blood-flow velocity analysis. Depth-resolved AO-SLO fluorescent images of microglia and cone photoreceptors are visualized in parallel with 469 nm and 663 nm reflectance images of the microvasculature and other structures. Additional applications of the new instrumentation are discussed.


Adaptive-optics SLO imaging combined with widefield OCT and SLO enables precise 3D localization of fluorescent cells in the mouse retina


Area Tematica : oct

AngioVue Optovue


AngioVue Optovue


Area Tematica : oct

Swept-source optical coherence tomography angiography for choroidal neovascularization after bevacizumab and photodynamic Q3 therapy


Swept-source optical coherence tomography angiography for choroidal neovascularization after bevacizumab and photodynamic Q3 therapy


Area Tematica : oct

Wideband Electrically Pumped 1050-nm MEMS-Tunable VCSEL for Ophthalmic Imaging


Wideband Electrically Pumped 1050-nm MEMS-Tunable VCSEL for Ophthalmic Imaging


Area Tematica : oct

Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers


Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers


Area Tematica : oct

ANGIOVUE OCT-Angiography (OCTA) system


ANGIOVUE OCT-Angiography (OCTA) system


Area Tematica : oct

Swept-Source OCT Angiography: SS OCT AngioTM


Swept-Source OCT Angiography: SS OCT AngioTM


Area Tematica : oct

Statistical analysis of motion contrast in optical coherence tomography angiography


Statistical analysis of motion contrast in optical coherence tomography angiography


Area Tematica : oct

A Review of Algorithms for Segmentation of Retinal Image Data Using Optical Coherence Tomograph


A Review of Algorithms for Segmentation of Retinal Image Data Using Optical Coherence Tomograph


Area Tematica : oct

Mathematical modeling and glaucoma: the need for an individualized approach to risk assessment


Mathematical modeling and glaucoma: the need for an individualized approach to risk assessment


Area Tematica : glaucoma

Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization


Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization


Area Tematica : oct

Combined eye gel containing sodium hyaluronate and xanthan gum for the treatment of the corneal epithelial defect after pterygium surgery


Combined eye gel containing sodium hyaluronate and xanthan gum for the treatment of the corneal epithelial defect after pterygium surgery


Area Tematica : congiuntiva

ARVO 2015 Annual Meeting Abstracts


ARVO 2015 Annual Meeting Abstracts


Area Tematica : oct

Improved microcirculation imaging of human skin in vivo using optical microangiography with a correlation mapping mask


Improved microcirculation imaging of human skin in vivo using optical microangiography with a correlation mapping mask


Area Tematica : oct

Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye


Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye


Area Tematica : oct

Optimization of the split-spectrum amplitude-decorrelation angiography algorithm on a spectral optical coherence tomography system


Optimization of the split-spectrum amplitude-decorrelation angiography algorithm on a spectral optical coherence tomography system


Area Tematica : oct

Automated choroidal neovascularization detection algorithm for optical coherence tomography angiography


Automated choroidal neovascularization detection algorithm for optical coherence tomography angiography


Area Tematica : oct

Swept-source OCT Angiography of the Retinal Vasculature using Intensity Differentiation Based OMAG Algorithms


Swept-source OCT Angiography of the Retinal Vasculature using Intensity Differentiation Based OMAG Algorithms


Area Tematica : oct

Complex differential variance algorithm for optical coherence tomography angiography


Complex differential variance algorithm for optical coherence tomography angiography


Area Tematica : oct

Technologies for Analyzing the Optic Disc, RNFL, and Macula

Optical Coherence Tomography By Lindsey S. Folio, BSc; Gadi Wollstein, MD; and Joel S. Schuman, MD


 Glaucoma can be characterized as a slowly progressing optic neuropathy that damages the retinal ganglion cells (RGCs) and their axons. This damage causes thinning of the retinal nerve fiber layer (RNFL), leads to cupping of the optic nerve head (ONH), and usually results in observable visual field loss. Because glaucomatous damage is irreversible, early detection is crucial for effective treatment through medical or surgical methods to halt further progression and preserve functional vision.

 Studies have shown that up to half of the RGCs could be damaged before defects are reported on the visual field.1 A more resolute, objective method of identifying glaucoma is therefore needed for at-risk patients. 


Technologies for Analyzing the Optic Disc, RNFL, and Macula


Area Tematica : glaucoma

ImageJ User Guide


ImageJ User Guide


Area Tematica : oct

Angio OCT, Dye Less Angiography, A New Approach of Age Related Macular Degeneration (ARMD)


Angio OCT, Dye Less Angiography, A New Approach of Age Related Macular Degeneration (ARMD)


Area Tematica : oct

Noninvasive Visualization and Analysis of the Human Parafoveal Capillary Network Using Swept Source OCT Optical Microangiography


Noninvasive Visualization and Analysis of the Human Parafoveal Capillary Network Using Swept Source OCT Optical Microangiography


Area Tematica : oct

Basic Technology and Clinical Applications of the Updated Model of Laser Speckle Flowgraphy to Ocular Diseases


Basic Technology and Clinical Applications of the Updated Model of Laser Speckle Flowgraphy to Ocular Diseases


Area Tematica : oct

”Great diagnostic potential”


”Great diagnostic potential”


Area Tematica : oct

ARVO 2015


ARVO 2015


Area Tematica : oct

OCT angiography by absolute intensity difference applied to normal and diseased human retinas

Abstract: We compare four optical coherence tomography techniques for noninvasive visualization of microcapillary network in the human retina and murine cortex. We perform phantom studies to investigate contrast-tonoise ratio for angiographic images obtained with each of the algorithm. We show that the computationally simplest absolute intensity difference angiographic OCT algorithm that bases only on two cross-sectional intensity images may be successfully used in clinical study of healthy eyes and eyes with diabetic maculopathy and branch retinal vein occlusion. ©2015 Optical Society of America OCIS codes: (110.4500) Optical coherence tomography; (170.4470) Ophthalmology; (170.3880) Medical and biological imaging; (280.2490) Flow diagnostics. 


OCT angiography by absolute intensity difference applied to normal and diseased human retinas


Area Tematica : oct

Small eyesdbig problems


Small eyesdbig problems


Area Tematica : malformazioni rare

Image-guided femtosecond laser–assisted cataract surgery in Peters anomaly type 2


Image-guided femtosecond laser–assisted cataract surgery in Peters anomaly type 2


Area Tematica : cataratta

Single suture iris-to-capsulorhexis fixation for in-the-bag intraocular lens subluxation


Single suture iris-to-capsulorhexis fixation for in-the-bag intraocular lens subluxation


Area Tematica : cataratta

The X Factors: Three areas that will improve refractive cataract surgery outcomes


The X Factors: Three areas that will improve refractive cataract surgery outcomes


Area Tematica : cataratta

Step by step: Clinical and practical implementation of laser-assisted cataract surgery


Step by step: Clinical and practical implementation of laser-assisted cataract surgery


Area Tematica : cataratta

Crossing the finish line: Launching your premium technology practice


Crossing the finish line: Launching your premium technology practice


Area Tematica : cataratta

ASCRS completes third annual Clinical Survey


ASCRS completes third annual Clinical Survey


Area Tematica : difetti di vista

Innovating advanced treatments to increase compliance and improve outcomes for glaucoma patients: diagnostics, novel therapies, and surgical options


Innovating advanced treatments to increase compliance and improve outcomes for glaucoma patients: diagnostics, novel therapies, and surgical options


Area Tematica : glaucoma

Driving laser vision correction outcomes, category growth, and confidence in today’s turbulent environment


Driving laser vision correction outcomes, category growth, and confidence in today’s turbulent environment


Area Tematica : cataratta

What do the recent technological advancements for femto cataract surgery mean?


What do the recent technological advancements for femto cataract surgery mean?


Area Tematica : cataratta

Elaborazioni Informatiche

La ricerca svolta nel periodo gennaio-settembre 2011 é composta dalle seguenti attività: 


1. Analisi dello stato dell’arte, in particolare del lavoro svolto nel biennio 2004-2006 dal gruppo coordinato dal Prof. Giovanni Frosoli del Dipartimento di Matematica Applicata dell’Università di Firenze. 

Nella sezione 2 presentiamo una rivisitazione critica di questo lavoro. 

2. Fase preliminare di studio della letteratura, delle tecniche e degli algoritmi esistenti nel campo dell’elaborazione di immagini digitali. 

3. Lavoro di consulenza nelle acquisizioni manuali delle immagini di prova, in particolare per quanto riguarda la calibrazione dei parametri di acquisizione. 

4. Scelta e sviluppo degli algoritmi per l’effettiva elaborazione delle immagini di prova a disposizione. Nella sezione 3 descriveremo in dettaglio i risultati conseguiti. 

5. Prima individuazione delle tecniche statistiche e degli algoritmi di classificazione. 

Nella sezione 4 concluderemo presentando i possibili approcci al momento ipotizzati al problema e definendo lo schema delle successive fasi del lavoro. 


Elaborazioni Informatiche


Area Tematica : oct

A review of optical coherence tomography angiography (OCTA)


A review of optical coherence tomography angiography (OCTA)


Area Tematica : oct

Scleretizzazione


Scleretizzazione


Area Tematica : oct
Ricerca Oculisti

Le Interviste per Oftalmologia domani

INTERVISTA CONGRESSO SOI 2016 - DOTT. AMEDEO LUCENTE